王新胜，男，教授。2002年本科毕业于河南师范大学生物技术专业，2005年在中国科学院武汉植物园获得硕士学位，2013年在南京中医药大学获得博士学位，2016-2017年在德国弗莱堡大学医学院访问学者。主要研究方向为中药资源与开发利用，重点研究中药资源分布与生态关系、中药化学成分分离与鉴定、体内外药理活性。目前，已在国际著名期刊Food Science and Human Wellness, Journal of Ethnopharmacology, Phytochemical Analysis, Industrial Crops & Products, Ultrasonics Sonochemistry, International Journal of Biological Macromolecules, Scientia Horticulturae, Journal of Food Science, Biological Trace Element Research, Chemistry & Biodiversity等发表学术论文24篇。
教育背景
2005~至今 教授，河南科技大学
教育经历
2010~2013 博士，南京中医药大学
2002~2005 硕士，中国科学院武汉植物园
1998~2002 本科，河南师范大学
研究方向：
药用植物资源分布与生态关系、化学成分分离与鉴定、体内外药理活性及作用机制等。
科研项目
1. 国家自然科学基金项目，U1804175，基于TGF-β1/Smad通路的巧玲花糖苷类物质抗肝纤维化及机制，2019/01-2021/12，48万元，结题，主持；
2. 河南省科技研发计划联合基金项目，232301420100，通过 TLR4/NF-κB 和 Nrf2/HO-1 信号通路研究巧玲花糖苷改善 NASH 机制，2024/01-2025/12，20万元，结题，主持；
3. 河南省科技副总，5万元，2026/01-2027/12，在研，主持；
4. 国家自然科学基金项目，U1604192，两种油用牡丹籽壳抗菌低聚茋类化学成分及抗菌作用机制研究，2017/01-2019/12，41万元，结题，排名第二；
5. 河南省科技研发计划联合基金项目，232103810055，巧玲花抗 2 型糖尿病活性成分的发现及作用机制，2024/01-2024/12，10万元，结题，排名第二。
学术成果
论文
1. Yanfang Wu, Jiameng Zhang, Ting Zhang, Chenyu Wang, Wanting Bi, Yanxia Wu, Pu Liu, Xinsheng Wang*. The Ethanol Extract of Syringa pubescensTurcz. Flower Ameliorates Inflammation Responses by Inhibiting the Expression of Cyclooxygenase-2/Inducible Nitric Oxide Synthase and the Release of Inflammatory Factors. Chemistry & Biodiversity,2025: 22(12): e00985.
2. Suya Zhang, Ting Zhang, Yitong Shi, Chenyu Wang, Wanting Bi, Yanxia Wu, Xinyi Guan, Pu Liu, Xinsheng Wang* and Yanfang Wu. An Eco-Friendly and Nondestructive Approach to Decolor the Flower Polysaccharide of Syringa pubescens Turcz. ChemistrySelect, 2025, 10, e00441.
3. Weidong Xu, Yanfang Wu*, Jiameng Zhang, Zichen Zhang, Xinyi Guan, Suya Zhang, Xinsheng Wang*, Pu Liu, Enguo Fan. Syringa pubescens Turcz ethyl acetate extract improves non-alcoholic steatohepatitis by regulating the Nrf2, IκBα and TGF-β1 signaling pathways. Food Science and Human Wellness 2025, 14: 9250244.
4. Zi-Chen Zhang, Yan-FangWu, Jian-Sheng Xiong, Xin-Yi Guan, Su-Ya Zhang, Xin-Sheng Wang. Purification of Phenylethanoid Glycosides from Syringa pubescens Turcz. via Macroporous Resins and Comparison of Biological Activity. Separation Science Plus, 2025, 8: e202400247.
5. Jiameng Zhang, Yanfang Wu*, Chenyu Wang, Weidong Xu, Zichen Zhang, Suya Zhang, Xinyi Guan, Xinsheng Wang*. The antioxidant, anti-inflammatory and analgesic activity effect of ethyl acetate extract from the flowers of Syringa pubescens Turcz. Journal of Ethnopharmacology 322 (2024) 117561.
6. Xinsheng Wang*, Jiameng Zhang, Panxu Wang, Yanlong Zhang, Qinyu Yang, Zichen Zhang, Zhanqiang Ma, Yanfang Wu, Junying Ma, Enguo Fan. Evaluation of alpha-glucosidase inhibition activity and glycosides in the Syringa pubescens Turcz from different geographical origin. Scientia Horticulturae, 2023, 320: 112198.
7. Weidong Xu, Jiameng Zhang, Yanfang Wu, Zichen Zhang, Xinsheng Wang*, Junying Ma*. Influence of Five Drying Methods on Active Compound Contents and Bioactivities of Fresh Flowers from Syringa pubescens Turcz. Molecules, 2023, 28, 7803.
8. Qinyu Yang, Xinsheng Wang*, Yanlong Zhang, Mengyuan Li, Panxu Wang, Jiameng Zhang, Kun Liu, Yanfang Wu, Guomin Shen and Zhanqiang Ma. Simultaneous Determination of Phenylethanoid Glycosides and Antioxidant Activity of Syringa pubescens Turcz. from Different Geographical Origin in China. Journal of Chromatographic Science, 2023, 61(8): 766-772.
9. Yanfang Wu, Qinyu Yang, Danjie Wang, Ruixue Deng, Miao Yu and Xinsheng Wang*. A comparative study of echinacoside, oleuropein content and antioxidant properties of different solvent extracts from Syringa pubescens Turcz. Pak. J. Pharm. Sci., 2022, 35: 35-40.
10. Yanfang Wu, Yindi Chu, Qinyu Yang, Mengjia Li, Miao Yu, Ruixue Deng, Kun Liu, Xinsheng Wang*, Enguo Fan. Response surface methodology optimised solvothermal system enables an efficient extraction of echinacoside and oleuropein from Syringa pubescens Turcz. Phytochemical Analysis. 2021, 32:1074–1081.
11. Xinsheng Wang*, Qinyu Yang, Yanfang Wu*, Jiameng Zhang, Yunyun Zhang, Xuefan Yang, Yahui Wang, Qinan Wu. The biosynthesis and accumulation of bioactive ingredient of Sparganium stoloniferum Buch.-Ham. in the presence of phenanthrene and pyrene. Industrial Crops & Products 172 (2021) 113970.
12. Xinsheng Wang*, Yanfang Wu, Jie Li, Aoxiang Wang, Guangyao Li, Xueli Ren, Weiping Yin. Ultrasound-assisted deep eutectic solvent extraction of echinacoside and oleuropein from Syringa pubescens Turcz. Industrial Crops & Products 151 (2020) 112442.
13. Yanfang Wu, Jie Li, Ruixue Deng, Hong Lu, Xinsheng Wang*. Optimisation of parameters, antioxidant activity, and component analysis of flavonoids from Ecliptae Herba. International Food Research Journal, 2020, 27(4): 745 – 753.
14. Xinsheng Wang*, Yanfang Wu, Fangfang Wang, Junpeng Yi, Yanping Zhang, Pu Liu, Qingshan Niu. Optimization of polysaccharide process from Fructus corni with box-behnken design and antioxidant capacity. Pak. J. Pharm. Sci., 2019, 32(4): 1537-1544.
15. Xinsheng Wang*, Yanfang Wu, Qinan Wu, Chengying Wu. Trace Elements Characteristic Based on ICP-AES and the Correlation of Flavonoids from Sparganii rhizome. Biological Trace Element Research, 2018 182: 381–386.
16. Yanfang Wu, Xinsheng Wang*, Enguo Fan. Optimisation of Ultrasound-assisted Extraction of Puerarin and Total Isoflavones from Puerariae Lobatae Radix (Pueraria lobata (Wild.) Ohwi) with Response Surface Methodology. Phytochem. Anal. 2012, 23, 513–519.
17. Yanfang Wu, Xinsheng Wang, Jintao Xue, Enguo Fan. Plant Phenolics Extraction from Flos Chrysanthemi: Response Surface Methodology Based Optimization and the Correlation Between Extracts and Free Radical Scavenging Activity. Journal of Food Science, 2017, 82: 2726-2733.
18. Yanfang Wu, Xinsheng Wang*, Pu Liu, Qingshan Niu, Qinan Wu. Quantitative Determination of Anthraquinones and Resveratrol in Polygonum Cillinerve (Nakai) Ohwi by HPLC-PAD. Journal of AOAC International. 2017, 100, 25-29.
19. Xinsheng Wang, Yanfang Wu, Qinan Wu, Yefei Qian, Wei Yue and Qiaoli Liang. Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry for Rapid Analysis of Seven Phenolic Compounds of Sparganii Rhizoma. Acta Chromatographica, 2015, 27: 755–766.
20. Xinsheng Wang, Yanfang Wu, Qinan Wu, Guangyun Chen, Wei Yue and Qiaoli Liang. Antioxidant activities in vitro and in vivo of water-soluble polysaccharide isolated from Sparganium stoloniferum Buch.-Ham. Pak. J. Pharm. Sci., 2015, 28:147-151.
21. Xinsheng Wang, Yanfang Wu, Qinan Wu, Guangyun Chen, Wei Yue and Qiaoli Liang. Optimisation of ultrasound assisted extraction of phenolic compounds from Sparganii rhizoma with response surface methodology. Ultrasonics Sonochemistry 2013,20: 846–854.
22. Xinsheng Wang, Yanfang Wu, Qinan Wu, Guangyun Chen, Wei Yue and Qiaoli Liang. Determination of Seven Phenolic Compounds in Rhizoma Sparganii by RP-HPLC. Journal of Chromatographic Science, 2013, 51: 371–375.
23. Xin-Sheng Wang, Yan-Fang Wu, Shi-Lin Dai, Rong Chen, Ying Shao. Ultrasound-assisted extraction of geniposide from Gardenia jasminoides. Ultrasonics Sonochemistry, 2012, 19: 1155–1159.
24. Xinsheng Wang, Qinan Wu, Yanfang Wu, Guangyun Chen, Wei Yue and Qiaoli Liang. Response Surface Optimized Ultrasonic-Assisted Extraction of Flavonoids from Sparganii Rhizoma and Evaluation of Their in Vitro Antioxidant Activities. Molecules, 2012, 17, 6769-6783.
专著
1. 尹卫平，王忠东，林瑞超，王新胜等著.《伏牛山药用植物志》(第2卷)，科学出版社，2010.4, ISBN: 9787030270238，撰写12万字。
2. 尹卫平主编，王新胜，刘军娜，郑英丽，刘坤，《伏牛山药用植物志》(第7卷)，科学出版社， ISBN: 9787030498496，撰写35万字，2016-09。
3. 郭旭明，韩建国，王新胜等编.《仪器分析》，化学工业出版社，2014.3, ISBN:9787122192455，撰写1.5万字。
4. Yanfang Wu, Xinsheng Wang, Enguo Fan*, Extraction, Structure, and Bioactivities of the Polysaccharides from Fructus. Book chapter in Polysaccharides: Bioactivity and Biotechnology (Edited by Jean-Michel Merillon and Kishan G. Ramawat), Springer Verlag, Germany, 2015. (DOI 10.1007/978-3-319-03751-6_2-1) (Book chapter)
专利
1. 巧玲花提取物在制备降血糖药物中的应用. 202310648957 .6 (实审中)
2. 巧玲花提取物在制备镇痛药物中的用途. 202311461597 .5 (实审中)
3. 巧玲花提取物在制备治疗肝炎的药物中的用途. 202311461611 .1 (实审中)
