基本信息
高嘉屿，河南科技大学副教授，硕士生导师，校青年学术带头人培养对象，中国侨联青委会委员。2004年本科毕业于中国医科大学临床医学专业，2005年获英国利物浦大学免疫学硕士学位，2010年在英国东伦敦大学健康与生命科学院获得博士学位，曾先后就职于英国利物浦大学（助教），东伦敦大学（博士后，讲师）开展研究工作。主要研究方向为抗癌天然药物的化学及药理机制、肿瘤相关病毒的免疫逃脱机制、抗氧化药物药理。目前，已在国际著名期刊Virology，Toxicology and applied pharmacology, Journal of Pharmaceutical and Biomedical Analysis等发表学术论文30余篇。
邮箱： J.Gao@haust.edu.cn
教育背景
教育经历：
2006~2010 博士生, 英国东伦敦大学，健康与生命科学院
2004~2005 硕士生，英国利物浦大学，医学院
1999~2004 本科，中国医科大学，临床医学专业
工作履历：
2012~至今 副教授，硕士生导师，河南科技大学
2011~2012 讲师，英国东伦敦大学，健康与生命科学院
2010~2012 博士后，英国东伦敦大学，合作导师：Prof. O. Corcoran 2005~2006 助教，英国利物浦大学，医学院
学术兼职：
Journal of Herbal Medicine, Editor
GP-TCM (Europe), Life Member
研究领域:
天然药物化学
抗癌药物药理
肿瘤相关病毒免疫学
抗氧化药物药理
科研项目：
国家自然科学基金联合项目，河南省科技攻关项目，河南省三区人才项目等。
学术成果：
Representive Publication
Jiangxia Hu, Jiayu Gao*, 2020. Validation of a HPLC Method for Flavonoid Contents in Spina Gleditsiae and Its Use to Illustrate the Various Quality of Cultivated Varieties. Natural Product Communications, 15(8): 1-5. DOI: 10.1177/1934578X20946258.
Jiangxia Hu, Jiayu Gao*, Zijun Zhao, Xiao Yang, 2020. Response surface optimization of polysaccharide extraction from Galla Chinensis and determination of its antioxidant activity in vitro. Food Science and Technology, DOI: 10.1590/fst.38619.
Jiangxia Hu, Jiayu Gao*, Zijun Zhao, Xiao Yang, Lan Chen, 2020. Extraction Optimization of Galla Turcica Polysaccharides and Determination of Its Antioxidant Activities In Vitro. Natural Product Communications, 15(3): 1-9. DOI: 10.1177%2F1934578X20911764.
Jiangxia Hu, Jiayu Gao*, Lan Chen, Xiao Yang, 2020. Multivariate Data Analysis Guided Identification of Anticancer Constituents of Spina Gleditsiae for Human Hepatoma Cells. Natural Product Communications, 15(3): 1-7. DOI: 10.1177%2F1934578X20911258.
Jiayu Gao*, Weiping Yin, Olivia Corcoran*, 2019. From Scutellaria barbata to BZL101 in Cancer Patients: Phytochemistry, Pharmacology, and Clinical Evidence. Natural Product Communications, 14(10): 1-12. DOI: 10.1177/1934578X19880645.
Jiayu Gao*, Jiangxia Hu, Dongyi Hu, Xiao Yang, 2019. A Role of Gallic Acid in Oxidative Damage Diseases: A Comprehensive Review. Natural Product Communications, 14(8): 1-9. DOI: 10.1177/1934578X19874174.
Xiao Yang, Ruixue Deng, Pu Liu, Jiangxia Hu, Wentian Niu, Jiayu Gao*, 2019. Secondary Metabolite Mapping Identifies Peony Episperm Inhibitors of Human Hepatoma Cells. Natural Product Communications, 14(7): 1-7. DOI: 10.1177/1934578X19860313.
Jiayu Gao*, Xiao Yang, Jiangxia Hu, Weiping Yin, 2019. Identification of Anticancer Compounds in Gallnuts Through PCA-constructed Secondary Metabolite Map. International Journal of Pharmacology, 15(4): 515-522. DOI: 10.3923/ijp.2019.515.522
Jiayu Gao*, Xiao Yang, Jiangxia Hu, Xiao Yang, 2019. Polysaccharides of Spina Gleditsiae, A Potential Treasure in Anticancer and Antioxidant Drug Discovery. International Journal of Pharmacology, 15(1): 144-150. DOI: 10.3923/ijp.2019.144.150
Huaqing Liu, Jiayu Gao, Biyu Lv, Qiangqiang Yang, Kun Liu, Weiping Yin*, 2018. Anti-pathogens constituents and novel ergosterol derivatives with the broad-spectrum germicidal substances from earthworm, Pheretima aspergillum. Tetrahedron. 74(42): 6079-6087.
Jiayu Gao*, Xiao Yang, Weiping Yin, Ming Li, 2018. Gallnuts: A Potential Treasure in Anticancer Drug Discovery., Evidence-based Complementary and Alternative Medicine, 4930371.
Jiayu Gao*, Xiao Yang, Pu Liu, Weiping Yin, 2016, Optimization of Ultrasonic-assisted Extraction of Polysaccharides from Scutellaria barbata and Determination of their Anticancer and Antioxidant Activities., International Journal of Pharmacology, 12(7): 754-759.
Jiayu Gao*, Xiao Yang, Weiping Yin, 2016, From Traditional Usage to Pharmacological Evidence: A Systematic Mini-Review of Spina Gleditsiae., Evidence-based Complementary and Alternative Medicine, 3898957.
Jiayu Gao, Weiping Yin*, 2016, Flower Essential Oil Composition of Chionanthus retusus Lindl.et Paxt., Chemistry of Natural Compounds, 52(5): 934-935.
Jiayu Gao, Yaling Jiang, Lanlan Niu, Haidi Li, Weiping Yin*, 2016, Novel Isoflavone from the Cockroach Periplaneta americana, Chemistry of Natural Compounds, 52(3): 413-416.
Lanlan Niu, Jiayu Gao, Haidi Li, Junna Liu, Weiping Yin*, 2016, Novel Skeleton Compound Allomyrinanoid A and two purine alkaloids from the adult of Allomyrina dichotoma L., Bioorganic & Medicinal Chemistry Letters. 26(2): 366-369.
Jiayu Gao, Wenyuan Li, Lanlan Niu, Ranran Cao and Weiping Yin*. 2015. Isolation and structural elucidation of novel antimicrobial compounds from maggots of Chrysomyis megacephalaFabriciu. Natural Product Research. 29(3): 239-246.
Jiayu Gao, Weiping Yin*, Ting Gao, Ruixue Deng and Xin Li. 2014. Two bioactive compounds from the Chinese Scorpion Buthusmartensii Karsch. Natural Product Research. 28(10): 698-703.
Jiayu Gao, Winston A Morgan, Alberto Sanchez-Medina and Olivia Corcoran*. 2011. The ethanol extract of Scutellaria baicalensis and its active compounds induce cell cycle arrest and apoptosis including upregulation of p53 and BAX in human lung cancer cells. Toxicology and Applied Pharmacology, 254:221-228.
Jiayu Gao, Huiying Zhao, Peter J Hylands and Olivia Corcoran*. 2010. Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells. Journal of Pharmaceutical and Biomedical Analysis, 53:723-728.
Jiayu Gao, Judy M Coulson, Adrian Whitehouse and Neil Blake*. 2009. Reduction in RNA levels rather than retardation of translation is responsible for the inhibition of MHC Class I antigen presentation by the glutamic acid rich repeat of Herpesvirus Saimiri ORF73. Journal of Virology. 83(1): 273-282.
Jiayu Gao, Alberto Sanchez-Medina, Barbara A. Pendry, Michael J. Hughes, Geoffrey P. Webb and Olivia Corcoran*. 2008. Validation of a HPLC method for flavonoid biomarkers in skullcap (Scutellaria) and its use to illustrate wide variability in the quality of commercial tinctures. Journal of Pharmacy and Pharmaceutical Science. 11(1): 77-87.
Weiping Yin, Wenlu Duan, Pu Liu, Jiayu Gao, 2015, Natural Products Chemistry and Chemical Industry, Being: Chemical Industry Press.
Weiping Yin, Fengmin Wu, Ruixue Deng, Jiayu Gao, Junleng Wang. 2013. Funiu Mountain Medicinal Flora (Volume V), Beijing: Science Press.
奖励与荣誉：
Gerald Blunden Award（USA，2020）；
GlaxoSmithKline PhD Scholarship Grant（UK，2007-2009）；
University PhD Scholarship（UK，2006-2010）；
ORSAS（UK，2004）
